TY - JOUR ID - 85743 TI - National Consensus on Diagnosis and Management Guidelines for Primary Immunodeficiency JO - Immunology and Genetics Journal JA - IGJ LA - en SN - AU - Abolhassani, Hassan AU - Tavakol, Marzieh AU - Chavoshzadeh, Zahra AU - Mahdaviani, Seyed Alireza AU - Momen, Tooba AU - Yazdani, Reza AU - Azizi, Gholamreza AU - Movahedi, Masoud AU - Hamidieh, Amir Ali AU - Behniafard, Nasrin AU - Nabavi, Mohammamd AU - Arshi, Saba AU - Bemanian, Mohammad Hassan AU - Fallahpour, Morteza AU - Shokri, Sima AU - Molatefi, Rasol AU - Sherkat, Roya AU - Shirkani, Afshin AU - Amin, Reza AU - Aleyasin, Soheila AU - Faridhosseini, Reza AU - Jabbari-Azad, Farahzad AU - Mohammadzadeh, Iraj AU - Ghaffari, Javad AU - Shafiei, Alireza AU - Kalantari, Arash AU - Mansouri, Mahboubeh AU - Mesdaghi, Mehrnaz AU - Babaie, Delara AU - Ahanchian, Hamid AU - Khoshkhui, Maryam AU - Soheili, Habib AU - Eslamian, Mohammad Hossein AU - Cheraghi, Taher AU - Dabbaghzadeh, Abbas AU - Tavassoli, Mahmoud AU - Nasiri Kalmarzi, Rasoul AU - Mortazavi, Seyed Hamidreza AU - Kashef, Sara AU - Esmaeilzadeh, Hossein AU - Tafaroji, Javad AU - Khalili, Abbas AU - Zandieh, Fariborz AU - Sadeghi-Shabestari, Mahnaz AU - Darougar, Sepideh AU - Behmanesh, Fatemeh AU - Akbari, Hedayat AU - Zandkarimi, Mohammadreza AU - Abolnezhadian, Farhad AU - Fayezi, Abbas AU - Moghtaderi, Mojgan AU - Ahmadiafshar, Akefeh AU - Shakerian, Behzad AU - Sajedi, Vahid AU - Taghvaei, Behrang AU - Safari, Mojgan AU - Heidarzadeh, Marzieh AU - Ghalehbaghi, Babak AU - Fathi, Seyed Mohammad AU - Darabi, Behzad AU - Bazregari, Saeed AU - Bazargan, Nasrin AU - Khayatzadeh, Alireza AU - Javahertrash, Naser AU - Bashardoust, Bahram AU - Zamani, Mohammadali AU - Mohsenzadeh, Azam AU - Ebrahimi, Sarehsadat AU - Sharafian, Samin AU - Vosughimotlagh, Ahmad AU - Tafakoridelbari, Mitra AU - Rahimi, Maziar AU - Ashournia, Parisa AU - Razaghian, Anahita AU - Aghaeimeybodi, Fatemeh AU - Mamishi, Setareh AU - Parvaneh, Nima AU - Rezaei, Nima AU - Aghamohammadi, Asghar AD - Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institute at Karolinska University Hospital Huddinge, Stockholm, Sweden AD - Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran AD - Pediatric Infections Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran AD - Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran AD - Department of Allergy and Clinical Immunology, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran AD - Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran, and the University of Medical Science, Tehran, Iran AD - Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran AD - Division of Allergy and Clinical Immunology, Department of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Tehran, University of Medical Sciences, Tehran, Iran AD - Hematology, Oncology and Stem Cell Transplantation Research Centre, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Allergy and Clinical Immunology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AD - Department of Allergy and Clinical Immunology, Rasool e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran AD - Department of Allergy and Clinical Immunology, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. AD - Department of Pediatrics, Bo-Ali children's Hospital of Ardabil University of Medical Sciences, Ardabil, Iran AD - Acquired Immunodeficiency Research Center, lsfahan University of Medical Sciences, Isfahan, lran AD - Allergy and Clinical Immunology Department, Bushehr University of Medical Science, School of Medicine, Bushehr, Iran AD - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AD - Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran AD - Noncommunicable Pediatric Diseases Research Center, Amirkola Hospital, Babol University of Medical Sciences, Babol, Iran AD - Department of Pediatrics, Mazandaran University of Medical Sciences, Sari, Iran AD - Department of Immunology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Immunology and Allergy, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Immunology and Allergy Department, Mofid Children's Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran AD - Department of Pediatrics, School of Medicine, Arak University of Medical Sciences, Arak, Iran AD - Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran AD - Department of Pediatrics, 17th Shahrivar Children's Hospital, Guilan University of Medical Sciences, Rasht, Iran AD - Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran AD - Cellular & Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran AD - Department of Pediatrics, Kermanshah University of Medical Sciences, Kermanshah, Iran AD - Department of Pediatrics, Qom University of Medical Sciences, Qom, Iran AD - Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AD - Department of Immunology and Allergy, Tabriz University of Medical Sciences, Tabriz, Iran AD - Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD) AD - Department of Immunology and Allergy, Ahvaz University of Medical Sciences, Ahvaz, Iran AD - Mousavi Hospital, Zanjan University of Meical Sciences, Zanjan, Iran AD - Department of Immunology and Allergy, Hormozgan University of Medical Sciences, Bandar Abbas, Iran AD - Department of Immunology and Allergy, Semnan University of Medical Sciences, Semnan, Iran AD - Department of Immunology and Allergy, Kashan University of Medical Sciences, Kashan, Iran AD - Department of Immunology and Allergy, Qazvin University of Medical Sciences, Qazvin, Iran AD - Department of Immunology and Allergy, Ilam University of Medical Sciences, Ilam, Iran AD - Department of Immunology and Allergy, Kerman University of Medical Sciences, Kerman, Iran AD - Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran AD - Department of Immunology and Allergy, Shahrekord University of Medical Sciences, Shahrekord , Iran AD - Department of Pediatrics, Lorestan University of Medical Sciences, Khorramabad, Iran AD - Department of Internal Medicine Shahid Sadoughi University of Medical Sciences, Yazd, Iran AD - Pediatric Infectious Diseases Research Center, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Science, Tehran, Iran AD - Iranian Primary Immunodeficiencies Network (IPIN), Tehran University of Medical Science, Tehran, Iran Y1 - 2019 PY - 2019 VL - 2 IS - 1 SP - 1 EP - 21 KW - Primary immunodeficiency KW - Symptoms KW - Management KW - consensus KW - guideline DO - 10.22034/igj.2019.85743 N2 - Primary immunodeficiency (PID) is a group of more than 400 distinct genetic disorders affecting both children and adults. As signs and symptoms of PID are usually heterogeneous and unspecific, based on the available human resources and laboratory facilities, diagnosis and follow-up of these patients can be challenging. In line with this notion, management and treatment of PID are practiced divergently in different PID centers. In order to reach a distinct national protocol and given the little evidence on appropriate or universal guidelines to improve the current status of management of the disease, the Iranian PID network designed a consensus suitable for regional resources. This review summarizes this PID guideline based on the importance of different clinical complications and the level of medical authority visiting those at the first line. Further, for each complication, appropriate interventions are mentioned to improve the approach. UR - http://www.igjournal.ir/article_85743.html L1 - http://www.igjournal.ir/article_85743_6ca16a5014f35825bb847691970b005f.pdf ER -